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Experience of picamilone application
in gerontopsychiatric practice
Novikov VE, Kovaleva LA.
[Article in Russian]
Institute of Clinical Psychiatry of the All-Union Centre of psychic health,
34, Kashirskoye highway, Moscow 115522, USSR
Abstract
The clinical investigation of the new native drug
picamilone related to the GABA- derivatives allowed to show together with characteristic nootropic effect also the pronounced antidepressive mainly stimulating effect.
The pronounced thymoleptic action of the drug is exhibited by administration in the doses of 60-120 mg in twenty-four hours and can be used for therapy of relatively not deep depressive states in old age.
Picamilone is preferable as an antidepressive drug in patients with neuroleptic side
effects. At more grave depressions the complex therapy together with antidepressants of tri and tetracyclic structure comes true.
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